Education
1998: BSc & MSc, Physics, University College London, UK
2002: Ph.D. Medical Physics and Bioengineering, University College London, London, UK
Academic Positions
2005-6: Instructor, Massachusetts General Hospital (Radiology), Harvard Medical School, Boston, MA
2006-2011 : Assistant Professor, Biomedical Engineering, Columbia University, New York, NY
2006-2011 : Assistant Professor, Radiology, Columbia University Medical Center, New York, NY
2008- : Mentor, Columbia University Graduate Program in Neurobiology and Behavior
2011-2013 : Associate Professor of Biomedical Engineering, Columbia University, New York, NY
2011-2013 : Associate Professor, Department of Radiology, Columbia University Medical Center
2013-2017 : Associate Professor (tenured) of Biomedical Engineering, Columbia University, New York, NY
2013-2017: Associate Professor (tenured), Department of Radiology, Columbia University Medical Center
2014- : Columbia Zuckerman Mind Brain Behavior Institute Investigator
2017- : Professor,Department of Biomedical Engineering, Columbia University, New York, NY
2017- : Professor, Department of Radiology, Columbia University Medical Center, New York, NY
Professional and Research Positions
2002-3: Manager of In Vivo Spectroscopy, Argose Inc., Waltham, MA
2003-5: Post-doctoral Research Fellow, Martinos Center for Biomedical Imaging (Radiology), Massachusetts General Hospital, Boston, MA
Professional Affiliations
Optical Society of America (OSA) (Elected Fellow 2015)
The International Society for Optical Engineering (SPIE) (Elected Fellow 2017)
American Institute for Medical and Biological Engineering (AIMBE) (Elected Fellow 2017)
Society for Neuroscience (SFN)
International Society for Cerebral Blood Flow and Metabolism (ISCBFM)
American Association of Physicists in Medicine (AAPM)
Society for Brain Mapping & Therapeutics (SBMT)
American Heart Association
Honors and Awards
Wood and Oliver Lodge undergraduate awards from University College London (1994-8)
Wellcome Trust Prize Studentship, Ph.D. Fellowship (1998-2002)
Wallace H Coulter Foundation Early Career Award (2006)
Human Frontier of Science Program Young Investigator Award (2007)
Rodriguez Junior Faculty Award, Columbia SEAS (2008).
Chair of Tissue Imaging and Spectroscopy Technical Group, Optical Society of America (2008-11)
NSF CAREER Award (2010)
Kavli Institute for Neuroscience at Columbia University Member (2011)
2011 Adolph Lomb Medal, Optical Society of America award for contributions to optics under age 35
2016 Fellow, OSA
2017 Fellow, SPIE
2017 Fellow, AIMBE
2018 SPIE 2018 Biophotonics Technology Innovator Award
Editorial Service (selected)
Associate Editor, IEEE Engineering in Medicine and Biology Society Annual Meeting 2008-
Special Issue Editor, Applied Optics: "Topics in Biomedical Optics 2008"
Review Editor, Frontiers in Neuroenergetics Journal 2008-
Topical Editor, Applied Optics (Biomedical Optics) 2009-2011
Special Issue Editor, Biomedical Optics Express 2010
Associate Editor, Biomedical Optics Express 2010-2013
Editorial Board Member, Journal of Biophotonics (Wiley) 2012-
Editorial Board Member, Biomedical Spectroscopy and Imaging Journal (IOS Press) 2012-
Associate Editor, Optica (OSA) 2014-2017
Associate Editor, Neurophotonics (SPIE) 2014-
Advisory Board, Current Opinion in Biomedical Engineering (Elsevier) 2016-
Conference Service (selected)
Program Committee, SPIE Optics East 2005 & 2006 Optical Methods in Drug Discovery and Development
Session Chair "Optics in Neuroscience" and Program Committee for National Institute of Health Fifth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside, 2006
Session Chair "Imaging brain function & disease", Lasers in Medicine & Biology Gordon Conference, 2006
Session Track Co-Chair, "Diagnostic Instrumentation & Physiological Measurements", IEEE Engineering in Medicine and Biology Conference 2006
Program Chair "Diffuse optical imaging and tomography", OSA BIOMED 2008
Associate Editor, "Biomedical Imaging and Image Processing" IEEE Engineering in Medicine and Biology Society Annual Meeting 2008-2011
Co-Chair "New Optical Instrumentation", World Molecular Imaging Congress 2008
Program Committee, IEEE Lasers and Electro-Optics Society (LEOS) Annual Meeting 2008
Program Committee, European Conference on Biomedical Optics 2009
Program Committee, "Neurons and Photons" conference at SPIE Photonics West 2009
Session Track Co-Chair, "Neural Engineering" IEEE Engineering in Medicine and Biology 2009
Session Chair, "In vivo optical imaging of animal disease models", Engineering Conferences International 2009.
Session Chair "Brain" and Program Committee for SPIE NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside, 2009
Co-Chair, Royal Society Conference "Making light work: Illuminating the future of biomedical optics" 2010
Program Chair "Biological and Drug Discovery Imaging", OSA BIOMED 2010
Chair of Engineering Conferences International (ECI)"Advances in Optics for Biotechnology, Medicine and Surgery XI" meeting 2011
Program Committee, SPIE "Optogenetics and hybrid-optical control of cells" meeting 2013
Co-Chair, "Neurophotonics" sub-conference at the OSA/SPIE European Conference on Biomedical Optics (ECBO 2013).
Co-Chair, "Biophysics, Biology and Biophotonics: the Crossroads", OSA BIOMED 2014
Co-Chair, "Neurophotonics", Engineering Conferences International (ECI) "Advances in Optics for Biotechnology, Medicine and Surgery" meeting 2015
Founding Chair, OSA Optics in the Brain, co-located with Optics in the Life Sciences, 2015,16,17
Subcommittee Chair, OSA Frontiers in Optics 'Optics in Biology and Medicine track' 2016
General Chair, OSA Biomed 2018 (vice-chair 2016)
Neurophotonics Program Track Co-Chair, SPIE BiOS annual meeting (with David Boas) (2018-)
Grant Support (selected)
NIH BRAIN Initiative (NINDS & NIMH) - PI (U01, RF1), Co-I (U19)
National Institute of Neurological Disorders and Stroke (NINDS) - PI (R21 & 3 x R01)
Simons Foundation Collaboration on the Global Brain
NSF CAREER Award - PI
Wallace H Coulter Foundation - PI (Young Investigator, Translational Research Partnership)
Human Frontiers Science Program - PI (Young Investigator)
The Kavli Foundation (pilot grant) (2)
National Eye Institute Co-PI (R01)
Department of Defense, Army Research Office (MURI contract co-investigator)
National Heart, Blood and Lung Institute (NHLBI) - subcontract Co-PI
National Institute of Biomedical Imaging and BioEngineering (NIBIB) - Phase I SBIR
National Cancer Institute (NCI) - U54 imaging core
National Institute of Arthritis, Musculoskeletal and Skin (NIAMS) - P30 imaging core
National Center for Advancing Translational Sciences (NCATS) - UL1 CTSA pilot grants phase I & II
Defense Advanced Research Projects Agency (DARPA) - Phase I SBIR contractor
Mentored Students Graduate Fellowships, NSF (4), NDSEG/ONR (1), BioIGERT (2), T32 Medical Scientist Training Program (3)
Publications
- Hillman E. M. C, PhD Thesis (2002), Download.
- Xu L, Li W, Voleti V, Hillman EMC†, Stuart Firestein†, "Widespread Receptor Driven Modulation in Peripheral Olfactory Coding". BioRxiv. Sep;08. (2019), †equal contribution..
- Montgomery MK†, Kim S†, Dovas A†, Patel K, Mela A, Humala N, Zhao H, Thibodeaux D, Shaik M, Ma Y, Grinband J, Chow D, Schevon C, Hillman EMC†, Canoll P†, "Glioma-induced alterations in neuronal activity and neurovascular coupling during disease progression". BioRxiv. Sep;10. (2019), †equal contribution.
- Voleti V, Patel KB, Li W, Perez Campos C, Bharadwaj S, Yu H, Ford C, Casper MJ, Yan RW, Liang W, Wen C, Kimura KD, Targoff KL, Hillman EMC. Real-time volumetric microscopy of in vivo dynamics and large-scale samples with SCAPE 2.0. Nature Methods. 16(10):1054-62. (2019).
- Anikeeva P, Boyden E, Brangwynne C, Cisse, II, Fiehn O, Fromme P, Gingras AC, Greene CS, Heard E, Hell SW, Hillman EMC, Jensen GJ, Karchin R, Kiessling LL, Kleinstiver BP, Knight R, Kukura P, Lancaster MA, Loman N, Looger L, Lundberg E, Luo Q, Miyawaki A, Myers EW, Jr., Nolan GP, Picotti P, Reik W, Sauer M, Shalek AK, Shendure J, Slavov N, Tanay A, Troyanskaya O, van Valen D, Wang HW, Yi C, Yin P, Zernicka-Goetz M, Zhuang X. Voices in methods development. Nat Methods. 2019;16(10):945-51.
- Hillman EMC, Voleti V, Li W, Yu H, “Light sheet microscopy in neuroscience”, Annu Rev Neurosci. 42:295-313 (2019).
- >Vaadia RD†, Li W†, Voleti V, Singhania A, Hillman EMC†, Grueber WB†. "Characterization of Proprioceptive System Dynamics in Behaving Drosophila Larvae Using High-Speed Volumetric Microscopy". Current Biology 29, 935–944 (2019) .†equal contribution.
- Hillman EMC, Voleti V, Patel K, Li W, Yu H, Perez-Campos C, Benezra SE, Bruno RM, Galwaduge PT. “High-speed 3D imaging of cellular activity in the brain using axially-extended beams and light sheets”. Curr Opin Neurobiol. 50:190-200. (2018) .
- Miller J, Wang ST, Orukari I, Prior J, Sudlow G, Su X, Liang K, Tang R, Hillman EMC, Weilbaecher KN, Culver JP, Berezin MY, Achilefu S. Perfusion-based fluorescence imaging method delineates diverse organs and identifies multifocal tumors using generic near-infrared molecular probes. J Biophotonics. 11(4):e201700232 (2018) .
- Shaik MA, Hillman EMC. “Skip the salt: your brain might thank you.”, Nat Neurosci. Feb;21(2):154-155. (News & Views) (2018).
- Nguyen HD, Ullmann JFP, McLachlan GJ, Voleti V, Li W, Hillman EMC, Reutens DC, Janke A, "Whole-volume clustering of time series data from zebrafish brain calcium images via mixture modeling"Stat Anal Data Min: The ASA Data Sci Journal,11:5–16. (2018)
- Marcu L, Hillman EMC. “In vivo Optical Imaging / Intravital Microscopy.”, J Biophotonics. Jun;10(6-7):760-761. (2017)
- Tang M, Gao G, Rueda CB, Awano T, Engelstad KM, Sanchez-Quintero M-J, Yang H, Li F, Li H, Su Q, Shetler KE, Jones L, McConathy J, Thibodeaux DN, Yu H, Seo R, Hillman EMC, Noebels JL, De Vivo DC, Monani UR, “Brain microvasculature defects and Glut1-deficiency syndrome averted by early repletion of the Glucose Transporter-1 protein”, Nature Communications, 8:14152. (2017).
- Lunardi C.N., Gomes A.J., Palepu S., Galwaduge P.T., and Hillman E.M.C, ‘PLGA nano/microparticles loaded with cresyl violet as a tracer for drug delivery: Characterization and in-situ hyperspectral fluorescence and 2-photon localization’. Materials Science and Engineering: C, 70, Part 1: p. 505-511. (2017)
- Ma Y, Shaik MA, Kozberg MG, Kim SH, Portes JP, Timerman D, Hillman EMC. "Resting-state hemodynamics are spatiotemporally coupled to synchronized and symmetric neural activity in excitatory neurons." Proceedings of the National Academy of Sciences. PNAS, 113 (52) E8463–E8471 (2016).
- Kozberg MG, Hillman EMC, "Neurovascular coupling develops alongside neural circuits in the postnatal brain", Neurogenesis, 3(1): p. e1244439 (2016).
- Ma Y, Shaik MA, Kim SH, Kozberg MG, Thibodeaux DN, Zhao HT, Yu H., and Hillman EMC, ‘Wide-field optical mapping of neural activity and brain haemodynamics: considerations and novel approaches’. Philos Trans R Soc Lond B Biol Sci. 371 p. 1705 (2016).
- Kozberg MG, Ma Y, Kim SH, A. SM, and Hillman EMC, "Rapid postnatal expansion of neural networks occurs in an environment of altered neurovascular and neurometabolic coupling". J Neurosci, , 36(25): 6704-6717 (2016).
- Kozberg M and Hillman E, "Chapter 10 - Neurovascular coupling and energy metabolism in the developing brain", in Progress in Brain Research, H.H. Kazuto Masamoto and Y. Katsuya, Editors. Elsevier. p. 213-242. (2016)
- Akassoglou K, Agalliu D, Chang CJ, Davalos D, Grutzendler J, Hillman EMC, Khakh BS, Kleinfeld D, McGavern DB, Nelson SJ, and Zlokovic BV, "Neurovascular and Immuno-Imaging: From Mechanisms to Therapies". Proceedings of the Inaugural Symposium. Front Neurosci, 10: p. 46. (2016)
- Chow DS, Horenstein CI, Canoll PD, Lignelli A, Hillman EMC, Filippi CG, Grinband J, “Glioblastoma Induces Vascular Dysregulation in Non-Contrast Enhancing Peritumoral Regions in Humans”, Am J Radiol, 206 (5), 1073-1081 (2016).
- Bouchard MB, Voleti V, Mendes C, Lacefield C, Grueber W, Mann R, Bruno R, Hillman EMC, “Swept, confocally aligned planar excitation (SCAPE) microscopy for ultra-fast, volumetric microscopy of behaving organisms”, Nature Photonics, 9, 113–119 (2015).
- Galwaduge PT, Kim SH, Grosberg LE, Hillman EMC, "Simple wavefront correction framework for two-photon microscopy of in-vivo brain," Biomed. Opt. Express 6, 2997-3013 (2015)
- Lacroix A, Toussay X, Anenberg E, Lecrux C, Ferreiros N, Karagiannis A, Plaisier F, Chausson P, Jarlier F, Burgess SA, Hillman EMC, Tegeder I, Murphy TH, Hamel E, and Cauli B, “COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex.” J Neurosci, 35(34): p. 11791-810. (2015).
- Chen L, Choyke PL, Wang N, Clarke R, Bhujwalla ZM, Hillman EMC, Wang G, and Wang Y, "Unsupervised deconvolution of dynamic imaging reveals intratumor vascular heterogeneity and repopulation dynamics". PLoS One, 9(11): p. e112143, (2014).
- Hillman EMC, "Out for Blood", Scientific American MIND, July / Aug (2014).
- Hillman EMC, "Coupling Mechanism and Significance of the BOLD Signal: A Status Report", Annual Reviews, Neuroscience, 37, (in press) (2014)..
- Chen BR2, Kozberg MG2, Bouchard MB2, Shaik MA2, Hillman EMC, "A critical role for the vascular endothelium in functional neurovascular coupling in the brain", JAHA, 3: e000787, (2014).
- Cayce JM, Bouchard MB, Chernov MM, Chen BR, Grosberg LE, Jansen ED, Hillman EMC, Mahadevan-Jansen A. "Calcium imaging of infrared-stimulated activity in rodent brain", Cell Calcium, 55 (4), 183-190 (2014).
- Qiu J, Baik AD, Lu XL, Hillman EMC, Zhuang Z, Dong C, Guo XE. A noninvasive approach to determine viscoelastic properties of an individual adherent cell under fluid flow. Journal of Biomechanics, 47 (6), 1537-1541 (2014).
- Rayshubskiy A, Wojtasiewicz TJ, Mikell CB, Bouchard MB, Timerman D, Youngerman BE, McGovern RA, Otten ML, Canoll, PD, McKhann II GM, Hillman,EMC. "Direct, intraoperative observation of ~0.1 Hz hemodynamic oscillations in awake human cortex: Implications for fMRI." NeuroImage, 87, 323-331, (2014)..
- Hillman, EMC. & Kozberg, M. G. "What secrets can functional MRI reveal about the developing infant brain?" Imaging in Medicine 5, 203-206, (2013).
- Kozberg M, Chen BR, De Leo SE, Bouchard MB, Hillman EMC, "Resolving the transition from negative to positive BOLD in the developing brain", PNAS, 110(11):4380-5 (2013).
- Amoozegar CB, Wang T, Bouchard MB, McCaslin AFH, Blaner WS, Levenson RM, Hillman EMC, "Dynamic contrast enhanced optical imaging of in-vivo organ function", J Biomed Opt, 17(9), 096003 (2012).
- Grosberg LE, Chen BR, Hillman EMC, "Simultaneous multi-plane in-vivo non-linear microscopy using spectral encoding", Optics Letters, 37(14), 2967-2969 (2012).
- Muldoon, TJ, Burgess SA, Chen BR, Ratner D, and Hillman EMC, "Analysis of skin lesions using laminar optical tomography". Biomed. Opt. Express, 3(7): p. 1701-1712 (2012).
- Qiu J, Baik AD, Lu L, Hillman EMC, Zhuang Z, Dong C, Guo XE, “Theoretical Analysis of Novel Quasi-3D Microscopy of Cell Deformation”, Cel. Mol. Bioeng, 5 (2), 165-172. (2012)
- Hillman EMC, Elson DS, Bigio IJ, Levenson RM, So PTC, “Advances in optics for biotechnology, medicine and surgery”, Biomed. Opt. Expr, 3 (3), pp. 531-532 (2012).
- Hillman EMC, Amoozegar CB, Wang T, McCaslin AFH, Bouchard MB, Mansfield JR, Levenson RM, “In-vivo optical imaging and dynamic contrast methods for biomedical research” Phil. Trans. Royal Soc A. 369 (1955), 4620-4643 (2011).
- Chen L, Chan TH, Choyke PL, Hillman EMC, Bhu-jwalla ZM, Chi CY, Wang G, Szabo Z, Wang, Y, “A Signal Deconvolution Tool for In Vivo Dynamic Contrast-enhanced Imaging of Complex Tissues”, Bioinformatics, Sep 15;27(18):2607-9 (2011).
- Grosberg LE, Radosevich AJ, Asfaha S, Yang X, Wang TJ, Hillman EMC, "Spectral characterization and unmixing of intrinsic contrast in intact normal and diseased gastric tissues using hyperspectral two-photon microscopy" PlosOne, 6(5): e19925 (2011).
- McCaslin AFH, Chen BR, Radosevich AJ, Cauli B, Hillman EMC, "In-vivo 3D morphology of astrocyte-vasculature interactions in the somatosensory cortex: implications for neurovascular coupling", J Cereb Blood Flow Metab, 31, 795-806 (Feature and Cover article) (2011).
- Chen BR, Bouchard MB, McCaslin AFH, Burgess SA, Hillman EMC, "High-speed vascular dynamics of the hemodynamic response", Neuroimage, 54 (2), 1021-1030 (2011).
- Baik AD, Lu XL, Qiu J, Huo B, Hillman EMC, Dong C, Guo XE, "Quasi-3D Cytoskeletal Dynamics of Osteocytes under Fluid Flow", Biophys J. 99 (9), 2812-2820 (2010).
- Taber KH, Hillman EMC, Hurley RA, "Optical Imaging: A New Window to the Adult Brain", Neuropsychiatry Clin Neurosci. 22 (4), 357-360 (2010). (cover)
- Nordstrom RJ, Almutairi A, Hillman EMC, "Feature Issue Introduction: Bio-Optics in Clinical Applications, Nanotechnology, and Drug Discovery", Biomed Opt Expr, 1 (3) 746-747 (2010).
- Burgess SA, Ratner D, Chen BR, Hillman EMC, "Fiber-Optic and Articulating Arm Implementations of Laminar Optical Tomography for Clinical Applications" Biomed Opt Expr, 1 (3), 780-790, (2010).
- Sun R, Bouchard MB, Hillman EMC "SPLASSH: Open source software for camera-based high-speed, multispectral in-vivo optical image acquisition" Biomed Opt Expr, 1 (2), 385-397 (2010).
- Tian P, Teng IC, May LD, Kurz R, Lu K, Scadeng M, Hillman EMC, De Crespigny AJ, D'Arceuil HE, Mandeville JB, Marota JJA, Rosen BR, Liu TT, Boas DA, Buxton R, Dale AM, Devor A, "Cortical depth-specific microvascular dilation underlies laminar differences in BOLD fMRI response", PNAS, 107 (34), 15246-15251 (2010).
- Sirotin Y. B, Hillman E. M. C, Bordier C, Das A. "Spatiotemporal precision and hemodynamic mechanism of optical point-spreads in alert primates", PNAS 106, 18390-18395, (2009).
- Burgess S. A and Hillman E. M. C, "Laminar Optical Tomography", Chapter in 'Handbook of Biomedical Optics'. Eds: Boas DA, Pitris C, Ramanujam N (Taylor & Francis). in press (2009)
- Bouchard M. B., Chen B. R, Burgess S. A, Hillman E. M. C, "Ultra-fast multispectral optical imaging of cortical oxygenation, blood flow and intracellular calcium dynamics", Optics Express, 17 (18), 15670-15678, (2009).
- Hillman E. M. C, Burgess S. A, Chen B. “Macroscopic molecular optical imaging of rodent brain”, Book Chapter in ‘Molecular Imaging of the Rodent Brain’ (Neuromethods Series), Editor. Bacskai B. J, Ed. In press 2009, Human Press (Springer).
- Blaner WS, O’Byrne SM, Wongsiriroj N, Kluwe J, D’Ambrosio D, Jiang H, Schwabe RF, Hillman E.M.C, Piantedosi R, Libien J. “Hepatic Stellate Cell Lipid Droplets: A Specialized Lipid Droplet for Retinoid Storage”, Biochimica et Biophysica Acta, 1791(6):467-73 (2009).
- Yuan B, Burgess SA, Iranmahboob AK, Bouchard MB, Lehrer N, Bordier C, Hillman EMC, "System for rapid, simultaneous, high resolution, depth-resolved fluorescence and absorption optical imaging", Rev. Sci. Instrum. 80, 043706-1 (2009).
- Karagiannis A, Gallopin T, David C, Battaglia D, Geoffroy H, Rossier J, Hillman E.M.C, Staiger J, Cauli B. “Classification of NPY-expressing neocortical interneurons", J. Neurosci, 29(11):3642-3659 (2009).
- Hillman E. M. C, Burgess S. A. "Sub-millimeter Resolution 3D Optical Imaging of Living Tissue using Laminar Optical Tomography", Laser & Photonics Reviews, 3 (1-2), 159-180, (2009).
- Devor A, Hillman E. M. C, Tian P, Waeber C, Teng I. C, Ruvinskaya S, Shalinsky M, Zhu H, Haslinger R, Narayanan S, Ulbert I, Dunn A. K, Lo E, Rosen B. R, Dale A. M, Kleinfeld D, Boas D. A, “Stimulus-induced changes in blood flow and 2-deoxyglucose uptake dissociate in ipsilateral somatosensory cortex", J. Neurosci, 28: 14347-14357 (2008).
- Burgess S. A, Bouchard M. B, Yuan B, Hillman E. M. C. “Simultaneous Multi-Wavelength Laminar Optical Tomography"Optics Letters, 33 (22), 2710-2712 (2008).
- Radosevich A. J, Bouchard M. B, Burgess S. A, Chen B. R, Hillman E. M. C. “Hyper-spectral in-vivo two-photon microscopy of intrinsic fluorophores”, Optics Letters, 33 (18), 2164-2166, (2008).*Also selected to appear in the Virtual Journal of Biomedical Optics, 3 (11), 2164 (cover) and the Virtual Journal of Biological Physics Research
- Hillman E. M. C and Moore A, "All-optical anatomical coregistration for small animal molecular imaging using dynamic contrast", Nature Photonics, 1 (9), 526 - 530, (2007).
- Hillman E. M. C, Bernus O, Pease E, Bouchard M. B. Pertsov A. “Depth-resolved optical imaging of transmural electrical propagation in perfused heart”, Optics Express, 15 (26), 17827-17841, (2007).
- Hillman E. M. C, "Optical Brain Imaging In-vivo: Techniques and Applications from Animal to Man" [Invited Review], J Biomed Opt, 12(5), 051402 (2007). *Also selected to appear in the “Virtual Journal of Biological Physics Research”
- Hillman E. M. C, Devor A, Bouchard M. B, Dunn A. K, Krauss G. W, Skoch J, Bacskai B. J, Dale A. M, Boas D. A, “Depth-resolved Optical Imaging and Microscopy of Vascular C ompartment Dynamics During Somatosensory Stimulation”, NeuroImage, 35(1): 89-104 (2007) '>Supplementary Data.
- Devor A, Tian P, Nishimura N, Teng IC, Hillman E. M. C, Narayanan S. N, Ulbert I, Boas D. A, Kleinfeld D, Dale A. M.“Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative BOLD”, J Neurosci, 27(16): 4452-4459. (2007) Supplementary Data
- Custo A, Wells W. M, Barnett A. H, Hillman E. M. C, Boas D. A,"Effective Scattering Coefficient of the Cerebral Spinal Fluid in Adult Head Models for Diffuse O ptical Imaging", Appl Opt. 45(19): 4747-4755 (2006).
- Zhang Q, Brukilacchio T. J, Li A, Stott J. J, Chaves T, Hillman E. M. C, Wu T, Chorlton M. A, Rafferty E, Moore R. H, Kopans D. B, Boas D. A., "Co-registere d Tomographic X-ray and Optical Breast Imaging: Initial Results." J Biomed Opt, 10(2), 024033-1-9 (2005).
- Corlu A, Choe R, Durduran T, Lee K, Schweiger M, Arridge S. R, Hillman E. M. C, Yodh A. G., "Diffuse optical tomography with spectral constraints and wavelength opt imization." Appl Opt, 44(11), 2082-2093 (2005)
- Li A, Boverman G, Zhang Y, Brooks D, Miller E. L, Kilmer M. E, Zhang Q, Hillman E. M. C, Boas D. A., "An optimal linear inverse solution given multiple priors in diffuse optical tomography." Appl Opt, 44(10), 1948-1956 (2005)
- Hillman, E. M. C, Boas, D. A, Dale, A. M, Dunn, A. K, "Laminar Optical Tomography: demonstration of millimeter-scale depth-resolved imaging in turbid media" Optics Letters, 29, (14), 1650-1652 (2004).
- Hillman, E. M. C, "Optical tomography", Book chapter in 'Optics Encyclopedia', Wiley-VCH. (Released December 2003).
- Corlu, A, Durduran, T, Choe, R, Schweiger, M, Hillman, E. M. C, Arridge, S. R. Yodh, A. G,>"Uniqueness and wavelength optimization in continuous-wave multispectral diffuse optical tomography” Optics Letters, 28, 23, 2339-2341 (2003).
- Hebden, J. C, Gonzalez, F. M, Gibson, A, Hillman, E. M. C, Yusof, R, Everdell, N, Delpy, D. T, Zaccanti, G, and Martelli, F, “Assessment of an in situ temporal calibration method for time-resolved optical tomography” Journal of Biomedical Optics 8, 87-92 (2003).
- Hebden,J. C, Gibson, A, Yusof, R, Everdell, N, Hillman, E. M. C, Delpy, D. T, Arridge, S. R, Austin, T, Meek, J. H, Wyatt, J. S, "Three-dimensional optical tomography of the premature infant brain” Phys. Med. Biol , 47, 23, 4155-4166 (2002).
- Hebden, J. C, Veenstra, H, Dehghani, H, Hillman, E. M. C, Schweiger, M, Arridge, S. R, nd Delpy, D. T, "Three dimensional time-resolved optical tomogr aphy of a conical breast phantom" Applied Optics 40 19, 3278-3287 (2001).
- Hillman, E. M. C, Hebden, J. C, Schweiger, M, Dehghani, H, Schmidt, F. E. W, Delpy, D. T, Arridge, S. R "Time Resolved Optical Tomography of the Human Forearm" Phys. Med. Biol, 46, 4, 1117-1130 (2001)
- Hillman,E.M.C, Hebden,J.C, Schmidt,F.E.W, Arridge,S.R, Schweiger,M, Dehghani,H, Delpy, D.T "Calibration techniques and datatype extraction for time-resolved op tical tomography" Rev Sci Instrum, 71, 9, 3415-3427 (2000).
- Schmidt, F. E. W, Hebden, J. C, Hillman, E. M. C, Fry ,M. E, Schweiger,M, Delpy,D. T "Multiple slice imaging of a tissue-equivalent phantom using time-resolved op tical tomography" Applied Optics 39, 19 3380-3387 (2000).
- Arridge, S. R., Hebden, J. C, Schweiger, M, Schmidt, FEW, Fry, M. E. Hillman, E. M. C, Dehghani,H "A method for 3D time-resolved optical tomography"A method for 3D time-resolved optical tomography" Imaging. Syst. Technol, 11, 2-11 (2000).
- Schmidt, F.E.W, Fry, M.E, Hillman, E.M.C, Hebden, J.C, and Delpy, D.T "A 32-channel time-resolved instrument for medical optical tomography" R ev. Sci. Instrum 71, 1, 256 - 265 (2000).
- Hebden, J.C, Schmidt, F.E.W, Fry, M.E, Schweiger, M, Hillman, E.M.C, Delpy, D.T, and Arridge, S. R "Simultaneous reconstruction of absorption and scatter ing images using multi-channel measurement of purely temporal data" Optics Letters, 24, 8, 534-536. (1999).
- Elwell, C.E, Springett, R, Hillman, E.M.C, Delpy,D.T "Oscillations in Cerebral Haemodynamics - Implications for Functional Activation Studies". Adv. Exp Med & Biol 471, 57-65 (1999).